Metaxās or Metaxa may refer to:

• Metaxas Line, fortifications in northeastern Greece in 1935–1940
• Metaxas, Greece, a village in the Greek region of Macedonia
• Metaxas Regime or 4th of August Regime, a short-lived authoritarian regime in Greece from 1936 to 1941

• Anastasios Metaxas (1862–1937), Greek architect and competitive marksman
• Andreas Metaxas (1790–1860), Greek politician
• Konstantinos Metaxas (1793–1870), Greek fighter of the Greek War of Independence and politician from Cephalonia
• Christina Metaxa (born 1992), Cypriot singer
• Dimitris Metaxas, Greek-American computer scientist
• Doris Metaxa (1911–2007), French tennis player
• Eric Metaxas (born 1963), American author
• Georges Metaxa (1899–1950), Romanian singer and actor
• Ioannis Metaxas (1871–1941), Greek general, prime minister and dictator
• Nemone Metaxas (born 1972), English DJ, presenter, producer, and athlete
• Nikolas Metaxas (born 1988), Cypriot singer

• Metaxa, a Greek brandy-based liqueur

• Georg von Metaxa (1914–1944), Austrian tennis player