McClean (listen^ⓘ) is an Irish surname. Notable people with the surname include:

• Adam McClean (born c. 1989), British journalist and broadcaster
• Andrew McClean, Irish Gaelic footballer
• Bernie Wright McClean (born 1979), Costa Rican professional footballer
• Christian McClean, English former professional footballer
• Francis McClean (1876–1955), pioneer aviator
• Frank McClean (1837–1904), astronomer and pioneer in spectrography
• James McClean (born 1989), Irish footballer playing for West Bromwich Albion
• Joe McClean (rugby league), rugby league footballer who has played in the 2010s
• John Gerard McClean (1914–1978), Bishop of Middlesbrough, 1967–78
• John Robinson McClean (1813–1873), British civil engineer and Liberal Party politician
• Mike McClean, British television presenter and actor
• Moses McClean (1804–1870), Democratic member of the U.S. House of Representatives from Pennsylvania
• Raymond McClean (1932–2011), Irish nationalist politician
• Sally McClean, Northern Irish statistician, computer scientist, and operations researcher
• Sheila McClean, Irish painter
• Shilo McClean, writer, researcher, public speaker, consultant
• Stacey McClean (born 1989), English singer and member of UK Pop band S Club
• Yolanda McClean, Canadian library technician and trade unionist

• Clan Maclean
• McClain (disambiguation)
• McClean Lake mine, a uranium mine in Saskatchewan, Canada
• McClean telescope, at the South African Astronomical Observatory
• MacLaine
• McLean (disambiguation)
• McLane (disambiguation)
• Macklin (disambiguation)