Manteo may refer to:

• Manteo, 1st Baron of Roanoke and Dasamongueponke, sixteenth-century American Indian leader involved with the Roanoke Colony
• Manteo, North Carolina, United States
• Manteo, Virginia, United States
• Manteo High School, North Carolina
• Lochmaeus manteo, a North American moth
• Manteo Elementary School, North Carolina
• Manteo to Murphy, an expression that means "across North Carolina"
• Navy Auxiliary Air Station Manteo, now Dare County Regional Airport, North Carolina