Manfred
prince of Sicily
Coat of arms of Aragonese Sicily
Duke of Athens & Neopatria
Reign	1312–1317
Predecessor	Roger Deslaur
Successor	William II, Duke of Athens
Born	1306
Died	9 November 1317 Trapani
Buried	Dominican church of Trapani
Noble family	of Barcelona
Father	Frederick II of Sicily
Mother	Eleanor of Anjou

Manfred (1306 – 9 November 1317), infante of Sicily, was the second son of Frederick III of Sicily and Eleanor of Anjou.

He was appointed Duke of Athens and Neopatria in 1312 by his father at the request of the knights of the Catalan Company then in control of Athens. Manfred was only five when he was named duke. His father sent Berenguer Estanyol as his regent.

In 1316, Alfonso Fadrique, Manfred's elder (but illegitimate) brother, was appointed vicar general of Athens. The young Duke never set foot in his realm, however, for he died in a fall from his horse before his twelfth birthday. He died in Trapani and was buried in the Dominican church located there. His younger brother William succeeded him as duke.

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