Macroscope may refer to:

• Macroscope (Wild-Leica), a type of optical microscope
• Macroscope (science concept), a method appropriate to the study of large objects or complex processes
• Macroscope (methodology suite), an integrated methodology suite for enterprise IT activities
• Macroscope (novel), a 1969 novel by Piers Anthony
• Macroscope (album), a 2014 album by the Nels Cline Singers

• Macroscopic scale
• Macroscopic limit
• Optical microscope
• Earth observation