Macon is a surname. It may be derived from French Maçon or Mâcon, meaning "marsh dweller"^{[citation needed]}, or a variant of the occupational surname Mason.^{[citation needed]}

People surnamed Macon or Maçon include:

• Daryl Macon (born 1995), American basketball player for Maccabi Tel Aviv of the Israeli Basketball Premier League
• David Harrison Macon (1870–1952), also known as Uncle Dave Macon, American country musician
• Eddie Macon (1927–2017), American National Football League and Canadian Football League player
• Gideon Macon (c. 1648–1702), early American settler and member of the House of Burgesses of Virginia
• Jeremy Maçon, 21st century Jersey politician
• Jean-Baptiste Maçon (fl. 1830–1834), merchant and political figure in Upper Canada
• Mark Macon (born 1969), American former basketball player
• Max Macon (1915–1989), American Major League Baseball player and minor league manager
• Nathaniel Macon (1758–1837), American politician
• Robert B. Macon (1859–1925), American politician
• Robert C. Macon (1890–1980), US Army general during World War II
• Valerie Macon (born 1950), American civil servant and eighth North Carolina Poet Laureate
• Yvann Maçon (born 1998), footballer from Guadeloupe

• Le Maçon, a list of people with the surname