Protein-coding gene in the species Homo sapiens
Calcium-binding protein 39 is a protein that in humans is encoded by the CAB39 gene .[ 5]
The protein encoded by this gene associates with STK11 (S erine/T hreonine K inase 11 ) and STRAD (ST E20-R elated AD aptor protein).[ 6] [ 6]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000135932 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036707 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Entrez Gene: CAB39 calcium binding protein 39" .^ a b Boudeau J, Baas AF, Deak M, Morrice NA, Kieloch A, Schutkowski M, Prescott AR, Clevers HC, Alessi DR (October 2003). "MO25α/β interact with STRADα/β enhancing their ability to bind, activate and localize LKB1 in the cytoplasm" . EMBO J . 22 (19): 5102–14. doi :10.1093/emboj/cdg490 . PMC 204473 PMID 14517248 .
External links
Further reading
Baas AF, Smit L, Clevers H (2004). "LKB1 tumor suppressor protein: PARtaker in cell polarity". Trends Cell Biol . 14 (6): 312–9. doi :10.1016/j.tcb.2004.04.001 . PMID 15183188 . Hawley SA, Davison M, Woods A, et al. (1996). "Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase" . J. Biol. Chem . 271 (44): 27879–87. doi :10.1074/jbc.271.44.27879 PMID 8910387 . Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics" . Genome Res . 10 (5): 703–13. doi :10.1101/gr.10.5.703 . PMC 310876 PMID 10810093 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Boudeau J, Baas AF, Deak M, et al. (2003). "MO25α/β interact with STRADα/β enhancing their ability to bind, activate and localize LKB1 in the cytoplasm" . EMBO J . 22 (19): 5102–14. doi :10.1093/emboj/cdg490 . PMC 204473 PMID 14517248 . Brajenovic M, Joberty G, Küster B, et al. (2004). "Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network" . J. Biol. Chem . 279 (13): 12804–11. doi :10.1074/jbc.M312171200 PMID 14676191 . Milburn CC, Boudeau J, Deak M, et al. (2004). "Crystal structure of MO25α in complex with the C terminus of the pseudo kinase STE20-related adaptor". Nat. Struct. Mol. Biol . 11 (2): 193–200. doi :10.1038/nsmb716 . PMID 14730349 . S2CID 18401688 . Lizcano JM, Göransson O, Toth R, et al. (2005). "LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1" . EMBO J . 23 (4): 833–43. doi :10.1038/sj.emboj.7600110 . PMC 381014 PMID 14976552 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Boudeau J, Scott JW, Resta N, et al. (2005). "Analysis of the LKB1-STRAD-MO25 complex" . J. Cell Sci . 117 (Pt 26): 6365–75. doi :10.1242/jcs.01571 PMID 15561763 . Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89. doi :10.1038/msb4100134 . PMC 1847948 PMID 17353931 .
