Luis Antonio Fernández de Córdoba y Spínola (Madrid, 20 September 1704 - Madrid, 14 January 1768), XI Duke of Medinaceli, X Duke of Feria, IX Duke of Alcalá de los Gazules, XI Duke of Segorbe, XII Duke of Cardona and X Count of Santa Gadea, was a Spanish aristocrat who served the Royal Spanish House.

He was the eldest son of Nicolás Fernández de Córdoba, 10th Duke of Medinaceli and Jerónima María Spínola y de la Cerda.

In addition to his many titles, he was Lieutenant General of the Royal Armies and Captain of the Royal Guard Company of the King.
In 1747, he was sent by King Ferdinand VI of Spain to Naples as Extraordinary ambassador, to act as godfather on behalf of the King, of the newborn Infante Felipe Pascual,son of the King of Naples and Sicily. For this, he received the collar of the Golden Fleece.
The King appointed him in 1749 Caballerizo mayor, a position he would hold under the new King Charles III of Spain, until the end of his life.
In 1766 he tried, without success, to mediate in the Esquilache Riots.

He married on 19 November 1722 with María Teresa de Moncada and Benavides (1707-1756) who would become, after the death of her father in 1727, the VII Duchess of Camiña, VII Marquise of Aytona, V Marquise of la Puebla de Castro and XI Countess of Medellín.They had 1 son and 3 daughters.

• Pedro de Alcántara Fernández de Córdoba y Montcada (1730-1789), his successor
• María del Rosario (1732 - 1773), married Francisco Ponce de León y Spínola, X Duke of Arcos.
• Ana María de la O (1738 - 1782), married Antonio de Benavides y de la Cueva, II Duke of Santisteban del Puerto.
• María Dolores (1746 - 1770)

In 1763 he remarried with María Francisca Pignatelli de Aragón y Gonzaga (1747-1769), daughter of Joaquín Pignatelli, Count of Fuentes. They had no children.

• Real Academia de la Historia.
• Fundacion Medinaceli