Lucius Calpurnius Piso (born Gnaeus Calpurnius Piso) was son of Gnaeus Calpurnius Piso (consul 7 BC) and Munatia Plancina.^[1] After his fathers suicide, he changed his name from Gnaeus to Lucius.^[2]

He was a member of the gens Calpurnia, one of Rome's most distinguished senatorial families, and specifically was among the Calpurnii Pisones.

His wife was Licinia, daughter of the consul Marcus Licinius Crassus Frugi. Their son was Gaius Calpurnius Piso who was the focal figure in the Pisonian conspiracy of AD 65, the most famous and wide-ranging plot against Emperor Nero, and who was ordered to commit suicide. ^{[citation needed]}