A lockdown is an emergency protocol that usually prevents people or information from leaving an area.

Lockdown or Lock Down may also refer to:

• Lockdown (South African TV series)
• Lockdown (1990 film)
• Lockdown (2000 film)
• Lockdown (2021 English film)
• Lockdown (2021 Nigerian film)
• 12 Rounds 3: Lockdown, a 2015 film
• Lockdown (2006 TV series), a National Geographic Channel show on prisons
• Lockdown (2020 TV series), a Canadian-American children's and teen streaming television series
• Lockdown (Bengali film), 2021 film

• "Lockdown" (The 4400)
• "Lockdown" (The Flash)
• "Lockdown" (Brooklyn Nine-Nine)
• "Lockdown" (Haven)
• "Lockdown" (House)
• "Lockdown" (Lost)
• "Lockdown" (Stargate SG-1)

• Lock Down, a 2002 album by Krosfyah
• "Lock Down", a 2016 song by Stooshe
• "Lockdown", a 2007 song by Alabama 3
• "Lock Down", a song by Cypress Hill from the 1993 album Black Sunday
• "Lock Down", a song by Guttermouth from the 1996 album Teri Yakimoto
• "Lock Down", a song by Jayo Felony from the 1995 album Take a Ride
• "Lock Down", a song by the Inner City Posse from the 1990 EP Bass-ment Cuts
• "Lockdown", a song by Amy Lee from the 2014 soundtrack Aftermath

• Lockdown (novel), a 2020 novel by Peter May
• "Lockdown" (poem), 2020 poem by Simon Armitage
• Lock-on (protest tactic) or lockdown
• Lockdown (Transformers), a fictional character
• Stay-at-home order or lockdown, a mass quarantine order
• TNA Lockdown, a TV wrestling event
• Tom Clancy's Rainbow Six: Lockdown, a 2005 video game