Kefalovryso (Greek: Κεφαλόβρυσο, "headspring"), in Katharevousa Kefalovryson (Κεφαλόβρυσον), may refer to several places in Greece:

• Kefalovryso, Argolis, a village in Argolis, part of the municipal unit Lyrkeia
• Kefalovryso, Ioannina, a village in the Ioannina regional unit, part of the municipal unit Ano Pogoni
• Kefalovryso, Larissa, a village in the Larissa regional unit, part of the municipality Elassona
• Kefalovryso, Messenia, a village in Messenia, part of the municipal unit Aristomenis
• Kefalovryso, Trikala, a village in the Trikala regional unit, part of the municipal unit Faloreia
• Mega Kefalovryso, a village in the Trikala regional unit, part of the municipal unit Faloreia