Kassandra may refer to:

• Cassandra, a character in Greek mythology
• 114 Kassandra, an asteroid
• Kassandra (Assassin's Creed), a fictional character in Assassin's Creed: Odyssey
• Kassandra, Chalkidiki, a modern municipality and peninsula in Chalkidiki, Greece
• Kassandra (TV series), a Venezuelan telenovela about a gypsy maiden marrying into a rich family

• Cassandra (disambiguation)
• Kassandra (name)