John Walton may refer to:

• John Walton (darts player) (born 1961), former BDO World Darts Champion and BDO World Masters Champion
• John Walton (Formula One), late Formula One team manager
• John Walton (footballer) (1928–1979), former English footballer with several clubs
• John Walton (American football) (born 1947), American football player
• John Walton (rugby league), rugby league footballer of the 1900s
• John Walton (cricketer) (1888–1970), English cricketer
• John Walton (sports broadcaster), American radio sports announcer

• John Walton (Continental Congress) (1738–1783), Georgia Continental Congressman, signer of the Articles of Confederation
• Sir John Lawson Walton (1852–1908), British MP and Attorney General of England and Wales
• Jack C. Walton (John Calloway Walton, 1881–1949), former governor of Oklahoma
• John Walton, Baron Walton of Detchant (1922–2016), British politician
• John Walton (Australian politician) (1927–1994), Victorian state politician

• John Walton (translator) (fl. 1410), English Augustinian canon and poet
• John Walton (bishop) (d. 1490?), English Augustinian abbot and archbishop of Dublin
• John Walton (botanist) (1895–1971), British botanist and paleobotanist
• John T. Walton (1946–2005), son of Walmart founder Sam Walton
• John Walton (actor) (1952–2014), Australian actor
• John Ike Walton, founding member of 13th Floor Elevators, a 1960s Texas rock group
• John H. Walton (born 1952), Old Testament Scholar, professor of Old Testament at Wheaton College
• John Isiah Walton (born 1985), American artist
• John K. Walton, professor specializing in the history of the development of tourism
• John Wilson Walton-Wilson (1823–1910), English architect. He changed his surname from John Wilson Walton to John Wilson Walton-Wilson in 1880, as a condition of a substantial legacy. His death certificate gives his surname as Wilson, but he used the double-barrelled name Walton-Wilson professionally, from 1880.
• John Walton (entomologist) (1784–1862), English entomologist
• John Walton (priest) (1565-1646), English Anglican priest

• John Walton, character in The $5,000,000 Counterfeiting Plot
• "John-Boy" Walton and John Walton Sr., characters on the US television series The Waltons