James Smith may refer to:

• James Smith (Australian rules footballer) (1899–1974), Australian rules footballer for Richmond Football Club
• James Smith (boxer) (born 1953), American boxer, nicknamed "Bonecrusher"
• James Smith (footballer, born 1844) (1844–1876), Scottish footballer, played in the first official international football match
• James Smith (footballer, born 1873) (1873–?), footballer
• James Smith (footballer, born 1908) (1908–1956), English left back who played for Doncaster Rovers, Lincoln City and Bradford City
• James Smith (footballer, born 1930) (1930–2022), English footballer for Chelsea and Leyton Orient
• James Smith (footballer, born 1985), English football player (Southport)
• James Smith (Scottish footballer) (fl. 1922), Scottish football player (Port Vale)
• James Smith (sports media figure) (born 1959), American boxer and host of In This Corner
• James Aikman Smith (1859–1931), Scottish rugby union player and referee
• James Crosbie Smith (1894–1980), English cricketer
• James R. Smith (1904–1986), American water polo player and coach
• Steve Smith (ice hockey, born April 30, 1963), Scottish-born Canadian ice hockey player
• James W. Smith (horse trainer) (1908–1969), American horse trainer
• James Smith (Leicestershire cricketer) (born 1977), English cricketer
• James Smith (New South Wales cricketer) (1880–1958), Australian cricketer
• James Smith (South Australia cricketer) (born 1988), Australian cricketer
• James Smith (Kent cricketer) (fl. 1792–1796), English cricketer
• James Smith (New Zealand cricketer) (1891–1971), New Zealand cricketer
• James Smith (sport shooter) (1931–2021), American Olympic shooter
• Jimmy Snuka (James Wiley Smith, 1943–2017), Fijian wrestler
• James Smith (Gaelic footballer) (born 1999), Irish Gaelic footballer
• James Smith (runner) (born 1913), American middle-distance runner, 1500 m runner-up at the 1937 USA Outdoor Track and Field Championships

• James Smith (Medal of Honor, 1864) (1826–1881), Medal of Honor recipient in the American Civil War
• James Smith (Medal of Honor, 1872) (1838–?), Medal of Honor recipient for peacetime actions
• James A. Smith (Medal of Honor) (1880–1944), Medal of Honor recipient in the Boxer Rebellion
• James Smith (VC) (1871–1946), English recipient of the Victoria Cross
• James Argyle Smith (1831–1901), Confederate general in the American Civil War
• James Alexander Smith (1881–1968), English recipient of the Victoria Cross
• James C. Smith (general) (1923–2016), U.S. Army general
• James Dunlop Smith (1858–1921), British official in the Indian Army
• James E. Smith (general) (born 1973), U.S. Space Force general
• James Floyd Smith (1884–1956), American test pilot and instructor for Glenn Martin
• James Robert Smith (RAF officer) (1891–?), World War I flying ace
• James Thomas Smith (1908–1990), U.S. Navy admiral
• James Smith (Texas general) (1792–1855), general in the Revolutionary Army of Texas
• James Smith (frontiersman) (1737–1813), American leader of the Black Boys Rebellion against British rule in colonial America
• James Webber Smith (1778–1853), British Royal Artillery officer
• James Webster Smith (1850–1876), first black cadet at West Point

• James Prince (James Andre Smith, born 1965), American founder of Texas-based Rap-A-Lot Records
• James Smith, American guitarist for the band Underoath
• James Smith, British singer and member of Hadouken!
• James Smith, British singer and member Yard Act
• James Smith (born 1999), finalist in Britain's Got Talent
• James Smith (actor) (born 1948), English actor
• James Marcus Smith, singer, better known as P. J. Proby
• James Thomas Smith, British musician and member of The xx, better known as Jamie xx
• LL Cool J (James Todd Smith, born 1968), American rapper

• James Smith (anaesthetist) (1917–1986), Scottish anaesthetist
• James Smith (Scottish botanist) (1763–1848), Scottish botanist
• James Smith (university principal) (1681–1736), Scottish principal of the University of Edinburgh, 1732–1736
• James Ernest Smith (1881–1973), founder and first president of the National Radio Institute in Washington, D.C.
• James Smith of Jordanhill (1782–1867), Scottish merchant, antiquarian, architect, geologist and biblical critic
• James Cuthbert Smith (born 1954), Director of Research at the Francis Crick Institute in London
• James Edward Smith (botanist) (1759–1828), English botanist and founder of the Linnean Society of London
• James Eric Smith (1909–1990), British zoologist
• James George Smith (1819–1849), American founder of Beta Theta Pi, a prominent college fraternity
• James Greig Smith (1854–1897), Scottish surgeon and medical author
• James K. A. Smith (born 1970), Canadian-born philosopher
• J. L. B. Smith (James Leonard Brierley Smith, 1897–1968), South African ichthyologist
• James Lorrain Smith (1862–1931), Scottish pathologist
• James Morton Smith (1919–2012), American historian
• James Perrin Smith (1864–1931), American geologist and paleontologist
• James Monroe Smith (academic administrator) (1888–1949), American educator and academic administrator in Louisiana
• James M. Smith, president of Eastern Michigan University

• James Smith (Pennsylvania politician) (1720–1806), Pennsylvania delegate who signed the United States Declaration of Independence
• James Strudwick Smith (1790–1859), U.S. Representative from North Carolina
• James Smith, 19th-century Canadian Cree Chief, founder of the James Smith First Nation in Saskatchewan
• James W. Smith Jr. (born 1943), American judge, Chief of the Supreme Court of Mississippi
• James Y. Smith (1809–1876), American, governor of Rhode Island
• James Monroe Smith (Georgia planter) (1839–1915), planter and state legislator in Georgia, U.S.
• James M. Smith (c. 1810–1898), New York City politician and judge
• James Smith Jr. (1851–1927), U.S. senator from New Jersey
• James A. Smith (mayor), first mayor of the city of Ridgefield, Washington
• James Smith (Kansas politician), Kansas secretary of state
• James H. Smith Jr. (1909–1982), U.S. assistant secretary of the Navy (AIR), 1953–1956, sailor and Olympic champion
• James Horace Smith (1852–1931), mayor of Orlando
• James Peyton Smith (1925–2006), Louisiana politician
• James Vernon Smith (1926–1973), U.S. representative from Oklahoma
• James C. Smith (politician) (born 1940), former Florida attorney general
• James T. Smith Jr. (born 1942), American, county executive of Baltimore County, Maryland
• James E. Smith (politician, born 1930) (1930–2020), comptroller of the currency of the United States, 1973–1976
• James E. Smith (Montana politician) (born 1948)
• James E. Smith Jr. (born 1967), member of the South Carolina House of Representatives
• James Smith (New Mexico politician), member of the New Mexico House of Representatives
• James F. Smith (Michigan politician) (1923–2007), member of the Michigan House of Representatives

• James Smith (1806–1868), lawyer, judge and political figure in Quebec
• James Smith (Canada West politician) (1811–1874), lawyer, judge and politician in Canada West
• James Sinclair Smith (1816–1897), Scottish-born Canadian politician
• James Edward Smith (politician) (1831–1892), mayor of Toronto
• James A. Smith (Canadian politician) (1911–1993), Canadian member of parliament
• James Smith (Yukon politician) (1919–2017), former commissioner of the Yukon Territory, 1966–1976

• James Smith (New South Wales politician) (1887–1962), former member of the New South Wales Legislative Assembly
• James Thorneloe Smith (1825–1902), engineer and politician in Queensland, Australia
• James Francis Smith (politician) (1844–1908), New South Wales politician
• James Joynton Smith (1858–1943), Australian politician
• James MacCallum Smith (1868–1939), Australian politician, newspaper proprietor and stock breeder
• James Norton Smith (1846–1911), Tasmanian politician
• James Vinton Smith (1897–1952), Australian politician

• James Smith (1587–1667), alderman of the City of London
• James Masterton-Smith (1878–1938), British civil servant
• James Parker Smith (1854–1929), British member of parliament for Glasgow Partick, 1890–1906

• James Francis Smith (1859–1928), U.S. administrator, governor of the Philippines, 1906–1909
• James Skivring Smith (1825–1892), U.S.-born vice president, 1870–1872, and interim president, 1871–1872, of Liberia
• James Skivring Smith Jr. (1891–1950), Liberian politician
• James Alfred Smith (1913–1993), British diplomat, chief justice of the Bahamas

• James Smith (archdeacon of Barnstaple) (died 1667), archdeacon of Barnstaple
• James Smith (archdeacon of Connor) (1800–1865), Anglican priest in Ireland
• James Smith (vicar-apostolic of the Northern District) (1645–1711), English Roman Catholic vicar-apostolic
• James Smith (moderator) (1803–1897), Church of Scotland minister and moderator of the General Assembly
• James Elishama Smith (1801–1857), British journalist and religious writer
• James Allwood Smith (1806–1882), American minister and state legislator
• James Smith (archbishop of St Andrews and Edinburgh) (1841–1928), Roman Catholic archbishop in Scotland
• James E. Smith (biblical scholar) (born 1939), American biblical scholar
• James K. A. Smith (born 1970), Canadian-American proponent of radical orthodoxy
• James Tuttle Smith (1870–1910), rector of the Church of the Resurrection in Manhattan

• James Smith (American physician) (1771-1841), American physician and vaccine expert
• James Smith, a character in the film 8 Mile
• James Smith (writer) (1775–1839), British humorist
• James Smith (gardener) (died 1789), gardener who journeyed to New Holland (Australia) in 1789
• James Smith (architect, died 1731) (c. 1645–1731), Scottish architect
• James Smith (Glasgow architect) (1808–1863), Scottish architect and father of Madeleine Smith
• James Smith (inventor) (1789–1850), British
• James Smith (journalist) (1820–1910), Australian journalist
• James Smith (miner) (1827–1897), Australian miner
• James Smith (draper) (1765–1823), close friend of Robert Burns
• James Smith (murderer) (1936–1962), English murderer
• James Smith (sculptor) (1775–1815), English sculptor
• James Allan Smith (1841–1918), dean of St David's
• James B. Smith (born 1952), dean of engineering, technology, and aeronautics at Southern New Hampshire University; former US ambassador to Saudi Arabia
• James Burrell Smith (1822–1897), English watercolour and landscape artist
• James Carmichael Smith (postmaster) (1852 – after 1914), postmaster in the Bahamas and Sierra Leone
• James Cooray Smith (born 1978), British writer, critic and columnist
• James E. Smith (engineer), computer engineer and professor at the University of Wisconsin–Madison
• James Edward Smith (murderer) (1952–1990), American murderer executed in Texas
• James J. Smith, American law enforcement officer
• James Kellum Smith (1893–1961), American architect
• James Lawrence Smith (1889–1950), co-owner of the Brooklyn Dodgers baseball team
• James Lindsay Smith (c. 1816–c. 1883), American slave narrative author and minister
• James Martin Smith (1892–1970), American civic, business, and religious leader in Arizona
• James McCune Smith (1813–1865), American physician & activist
• James Milton Smith (1823–1890), American soldier & politician
• James Robert Smith (author) (born 1957), American author
• James Thorne Smith (1892–1934), American author
• James W. Smith (trade unionist) (1838–1903), American labor unionist
• James John Smith (1892–1983), Irish applied mathematician and electrical engineer
• James Charles Smith, engineer
• James Cowan Smith (1843–1919), British civil engineer and philanthropist
• James Reuel Smith (1852–1935), American photographer and amateur historian
• James Smith (fitness influencer) (born 1989), England-born personal trainer and social media influencer
• James Smith, film editor, see James and Rose Smith

• James Smith Cree Nation, Saskatchewan, Canada
  • James Smith 100, an Indian reserve
• James Smith & Sons, an umbrella shop in London
• Sir James Smith's School, a secondary school in Camelford, North Cornwall, England

• Epitaph for James Smith, a 1785 satirical Scots epitaph written by poet Robert Burns
• Jim Smith (disambiguation)
• Jimmy Smith (disambiguation)
• Jamie Smith (disambiguation)
• James Smyth (disambiguation)