Isha may refer to:

• Isha (Fantasy), a fictional deity from Warhammer Fantasy
• Isha Foundation, a non-profit organization founded by Sadhguru Jaggi Vasudev
• Isha prayer, the Islamic night-time daily prayer
• Isha Upanishad, the Hindu religious text
• International Students of History Association (ISHA)
• Storm Isha, part of the 2023–24 European windstorm season

• Isha Basant Joshi (1908-?), Indian author
• Isha Chawla (born 1988), Indian film actress
• Isha Datar (born 1988), Canadian biotechnologist
• Isha Johansen (born 1964), Sierra Leonean entrepreneur
• Isha Judd (born 1962), Australian writer
• Isha Khan Choudhury (born 1971), Indian politician
• Isha Koppikar (born 1976), Indian actress
• Isha Lakhani (born 1985), Indian tennis player
• Isha Rikhi (born 1993), Indian film actress
• Isha Sesay (born 1976), American journalist
• Isha Sharvani (born 1984), Indian dancer
• Isha Talwar (born 1987), Indian film actress
• Isha Diwan, fictional villain played by Kajol in the 1997 Indian film Gupt

• Ishvara, a concept in Hinduism
• Eeshwar (disambiguation)
• Esha (disambiguation)
• Isa (disambiguation)
• Ish (disambiguation)