Ioannidis or Ioannides (Greek: Ιωαννίδης) is a Greek surname. The female version of the name is Ioannidou or Ioannides. Ioannidis or Ioannides is a patronymic surname which literally means "the son of Ioannis (Yiannis)", thus making it equivalent to English Johnson. Notable people with surname Ioannidis or Ioannides include:

• Alkinoos Ioannidis (born 1969), Cypriot composer and singer
• Andreas Ioannides (footballer) (born 1975), Cypriot football player
• Dimitrios Ioannides (1923–2010), military officer involved in the Greek military junta of 1967–1974
• Evgenios Ioannidis (born 2001), Greek chess player
• Fotis Ioannidis (born 2000), Greek footballer
• Georgios Ioannidis (born 1988), Greek footballer
• Giannis Ioannidis (1945–2023), former basketball coach and politician
• John Ioannidis (born 1965), medical researcher
• Matt Ioannidis (born 1994), American football player
• Nikolaos Ioannidis (born 1994), Greek footballer
• Paul Ioannidis (1924–2021), pilot and resistance fighter
• Perikles Ioannidis (1881–1965), admiral and second husband of Princess Maria Georgievna of Greece and Denmark
• Vassilis Ioannidis (born 1967), Greek footballer

• Mairi Ioannidou (born 1952), Greek Olympic swimmer
• Noni Ioannidou (born 1958), Greek actress and model
• Sarah Ioannides (born 1972), music director and conductor of the El Paso Symphony Orchestra
• Yiota Ioannidou (born 1971), Cypriot sculptor