Indianapolis Hoosiers was the name of three major league and at least three minor league baseball clubs based in Indianapolis.

• Indianapolis Hoosiers (American Association), which played in 1884
• Indianapolis Hoosiers (National League), which played from 1887 until 1889
• Indianapolis Hoosiers (Federal League), which played in 1914 and then became the Newark Peppers
• Indianapolis Hoosiers (minor league baseball), which played in the Western League before 1900, in the non-major American League during 1900, and in the Western Association in 1901

• Indiana Hoosiers, athletic teams representing Indiana University