Hisashi Matsuda (松田 久, 2 March 1924 - 13 November 2011)^[1] was a Japanese physicist known for his work in ion optics and mass spectrometry, specifically known for his contributions to instrument design.^[2]

Matsuda was born in Osaka and studied physics and mathematics at Osaka University, receiving a PhD in 1957 from Osaka University for his thesis on mass spectrometry under Koreichi Ogata.^[2] He started as assistant professor in 1955 and become associate professor in 1959 and full professor 1963 at Osaka University.^[2] His career was devoted to mass spectrometry, developing novel ion optics and improving resolving power.^[2] In 1956 he constructed the Ogata–Matsuda type instrument with a mass resolution of 900,000 which was the highest resolution worldwide.^[1] He constructed mass spectrometers suited for analysis of large biomolecules and was one of the first to realize the implications of mass spectrometry on the analysis of peptides and proteins.^[2] He retired in 1987.

He was awarded several prizes for his work, including the Nishina Memorial Prize in 1969 and the Toray Science and Technology Prize in 1982.^[1] He received the Thomson medal from the International Mass Spectrometry Society in 1991 and the Order of the Rising Sun, Gold Rays with a Neck Ribbon in spring 2002.^[1]

• Takayama, Mitsuo (2015). "Hisashi Matsuda". The Encyclopedia of Mass Spectrometry. Elsevier. pp. 145–146. doi:10.1016/B978-0-08-100379-4.00133-7. ISBN 9780081003794.