This is a list of secondary highways in Nipissing District, many of which serve as logging roads or provide access to Algonquin Park and sparsely populated areas in the Nipissing District of northeastern Ontario.

Highway 523
Route information
Maintained by the Ministry of Transportation of Ontario
Length	20.1 km[1] (12.5 mi)
Major junctions
South end	Nipissing–Hastings boundary
North end	Highway 60 – Madawaska
Location
Country	Canada
Province	Ontario
Districts	Nipissing
Highway system
Ontario provincial highways Current Former 400-series
← Highway 522B → Highway 524

Secondary Highway 523, commonly referred to as Highway 523, is a provincially maintained highway in the Canadian province of Ontario. The highway is a 20.1-kilometre (12.5 mi) north–south route in Nipissing District which follows the historic Madawaska Colonization Road. The highway begins at the Nipissing-Hastings boundary, where it continues south to Highway 127. It ends at Highway 60 in the village of Madawaska.

Highway 531
Route information
Maintained by Ministry of Transportation of Ontario
Length	13.5 km[1] (8.4 mi)
Existed	1956[2]–present
Major junctions
South end	Maple Road in Bonfield
North end	Highway 17 – Ottawa
Location
Country	Canada
Province	Ontario
Divisions	Nipissing District
Villages	Bonfield
Highway system
Ontario provincial highways Current Former 400-series
← Highway 529A → Highway 532

Secondary Highway 531, commonly referred to as Highway 531, is a provincially maintained secondary highway in the Canadian province of Ontario. It connects Highway 17 east of North Bay with the community of Bonfield. The 3.5-kilometre (2.2 mi) route was established in 1956, and has remained the same since then. It passes through a forested area and has several private residences located along its length. Aside from Maple Road, its southern terminus, and Highway 17, its northern terminus, Highway 531 encounters no roads along its length.

Highway 533
Route information
Maintained by Ministry of Transportation of Ontario
Length	53.4 km[1] (33.2 mi)
Existed	1956[2]–present
Major junctions
South end	Highway 17 in Mattawa
Major intersections	Highway 656
North end	Highway 63 near Eldee
Location
Country	Canada
Province	Ontario
Divisions	Nipissing District
Towns	Mattawa
Highway system
Ontario provincial highways Current Former 400-series
← Highway 532 → Highway 534

Secondary Highway 533, commonly referred to as Highway 533, is a provincially maintained secondary highway in the Canadian province of Ontario. The route begins in the town of Mattawa, at Highway 17, and travels north to Highway 63.

Highway 539
Route information
Maintained by the Ministry of Transportation of Ontario
Length	36.9 km[1] (22.9 mi)
Major junctions
Southwest end	Highway 17 in Warren
Major intersections	Highway 539A in River Valley
Northeast end	Highway 64 in Field
Location
Country	Canada
Province	Ontario
Divisions	Sudbury District, Nipissing District
Major cities	Markstay-Warren, West Nipissing
Highway system
Ontario provincial highways Current Former 400-series
← Highway 538 → Highway 539A

Secondary Highway 539, commonly referred to as Highway 539, is a secondary highway in the Canadian province of Ontario, located within the Sudbury and Nipissing Districts. Commencing at a junction with Highway 17 in the community of Warren, the highway extends northeasterly for 23.3 kilometres (14.5 mi) to the community of River Valley, and thence southeasterly for 13.6 kilometres (8.5 mi) to a junction with Highway 64 in Field.

A spur route, Highway 539A, extends northwesterly from Highway 539 at River Valley.

Highway 539A
Route information
Maintained by the Ministry of Transportation of Ontario
Length	5.8 km[1] (3.6 mi)
Existed	1958–present
Major junctions
Southeast end	Highway 539 in River Valley
Northwest end	Highway 805 at the Sudbury–Nipissing boundary
Location
Country	Canada
Province	Ontario
Divisions	Nipissing District
Towns	West Nipissing, River Valley
Highway system
Ontario provincial highways Current Former 400-series
← Highway 539 → Highway 540

Secondary Highway 539A, commonly referred to as Highway 539A, is a provincially maintained secondary highway in the Canadian province of Ontario, located within Nipissing District. Commencing at a junction with Highway 539 in the community of River Valley, the highway extends northwesterly for 13.1 kilometres (8.1 mi) to a point near where the Sturgeon River crosses the boundary between Nipissing and Sudbury District. At this point, the roadway turns northward and continues as Highway 805.

Highway 575
Route information
Maintained by the Ministry of Transportation of Ontario
Length	20.0 km[1] (12.4 mi)
Major junctions
Northeast end	Highway 17 in Verner
Northwest end	Highway 64 in Field
Location
Country	Canada
Province	Ontario
Divisions	Nipissing District
Towns	West Nipissing, Verner, Field
Highway system
Ontario provincial highways Current Former 400-series
← Highway 574 → Highway 577
Former provincial highways Highway 576  →

Secondary Highway 575, commonly referred to as Highway 575, is a secondary highway in the Canadian province of Ontario, located within Nipissing District. Commencing at Highway 17 in Verner, the highway travels to Highway 64 in the community of Field, a distance of 20.0 km (12.4 mi).

Highway 630
Route information
Maintained by the Ministry of Transportation of Ontario
Length	27.7 km[1] (17.2 mi)
Existed	July 28, 1961[3]–present
Major junctions
South end	Algonquin Park Access Point #29 at Kiosk
North end	Highway 17 / TCH near Eau Claire Station
Location
Country	Canada
Province	Ontario
Divisions	Nipissing District
Highway system
Ontario provincial highways Current Former 400-series
← Highway 628 → Highway 631

Secondary Highway 630, commonly referred to as Highway 630, is a secondary highway in the Canadian province of Ontario. It provides access to Algonquin Provincial Park from the north at Kioshkakwi Lake. It is 27.7 kilometres (17.2 mi) in length and links Highway 17 with the community of Kiosk. It was assumed as a provincial route on July 28, 1961, by which time it was paved north of Eau Claire.^[3]

Highway 656
Route information
Maintained by the Ministry of Transportation of Ontario
Length	3.7 km[1] (2.3 mi)
Existed	April 8, 1965[4]–present
Major junctions
South end	Highway 533 near Mattawa
North end	Otto Holden Generating Station
Location
Country	Canada
Province	Ontario
Divisions	Nipissing District
Towns	Mattawan Township
Highway system
Ontario provincial highways Current Former 400-series
← Highway 655 → Highway 657

Secondary Highway 656, commonly referred to as Highway 656, is a secondary highway in the Canadian province of Ontario. It provides access to the Otto Holden Generating Station on the Ottawa River from a junction with Highway 533 located just north of Mattawa, a distance of 3.7 kilometres (2.3 mi). It was established on April 8, 1965.^[4]