Heartstrings or Heart Strings may refer to:

• The chordae tendineae

• Heart Strings (1917 film), an American drama film directed by Allen Holubar
• Heart Strings (1920 film), an American drama film directed by J. Gordon Edwards
• Heartstrings (1923 film), a British silent romance film
• Heartstrings (2009 film), a British animated film
• Heartstrings (2016 film), a French romantic comedy
• Heartstrings (South Korean TV series), a 2011 South Korean television series
• Heartstrings (American TV series), an American anthology television series
• Heartstrings (Hong Kong TV series), a 1994 Hong Kong television series, starring Aaron Kwok and Gigi Lai

• The Heartstrings, earlier name of The Heartbeats

• Heart String (Earl Klugh album), 1978
• Heartstrings (Howling Bells album), 2014
• Heartstrings (Leighton Meester album), 2014
• Heartstrings (Willie P. Bennett album), 1999
• Heart Strings (Linda Lewis album), 1974
• Heart Strings (Bonnie Tyler album), 2003
• Heart Strings (Moya Brennan album), 2008

• "Heartstrings" (Janet Leon song), 2013
• "Heart Strings" by Oh Wonder from Ultralife, 2017
• "Heartstrings" by Leighton Meester from Heartstrings, 2014
• "Heartstrings" by Berlin from Count Three & Pray, 1986
• "Heartstrings" by M-22 featuring Ella Henderson, 2022

• String (disambiguation)