Ghost, in comics, may refer to:

• Ghost (Dark Horse Comics), a superhero and star of her own series, published in the 1990s and revived in 2012
• Ghosts (comics), an anthology of tales of the supernatural
• Ghost (Marvel Comics), a supervillain and foe of Iron Man
• Ghost (Nedor Comics), a Nedor Comics superhero from the Golden Age of Comics
• Ghost, a foe of Captain Atom in Charlton and later DC Comics

• Ghost Girl, a Marvel Comics character
• Ghost Rider
  • The Phantom Rider, a Western-themed character originally known as the Ghost Rider
• The Gay Ghost or the Grim Ghost, a DC Comics character
• Gentleman Ghost or the Ghost, a DC Comics villain
• The Grim Ghost, an Atlas/Seaboard Comics character
• Casper the friendly ghost, in Harvey Comics
• Ghost (disambiguation)