GWR may refer to:

• Great Western Railway, British railway company 1833–1947
• Great Western Railway (train operating company), British railway company (1996–)
• Great Western Main Line, a railway line in the UK
• Great Western Railway (disambiguation), other railway companies and routes with the name
• Gloucestershire Warwickshire Railway, an English heritage railway
• Aura Airlines (ICAO airline code: GWR), a Spanish airline
• Gwinner–Roger Melroe Field (FAA airport code: GWR), Sargent County, North Dakota, USA

• GWR Group, a defunct British commercial radio company, merged into GCap Media in 2005
  • GWR FM (Bristol & Bath)
  • GWR FM Wiltshire
• GWR Records, a British record label
• Graswurzelrevolution, a German anarcho-pacifist magazine
• Guinness World Records

• Geographically weighted regression
• Gwere language (ISO 639 language code: gwr)
• Llygad Gŵr, 13th-century Welsh poet

• All pages with titles beginning with GWR
• All pages with titles containing GWR