Frank Wilson may refer to:

• Frank Wilson (director) (1873–?), British actor, writer and film director
• Frank H. Wilson (1886–1956), African American actor
• Frank Wilson (Australian actor) (1924–2005), Australian actor
• Frank Avray Wilson (1914–2009), British artist
• Frank Wilson (musician) (1940–2012), songwriter and record producer for Motown Records
• Frank Wilson (journalist) (born 1941), retired book editor of the Philadelphia Inquirer
• J. Frank Wilson, American singer

• Frank Wilson (politician) (1859–1918), Premier of Western Australia
• Frank O'Brien Wilson (1883–1962), Royal Navy officer, later settled in Kenya
• Frank Wiley Wilson (1917–1982), United States federal judge
• Frank J. Wilson (judge) (died 1990), American judge in Illinois
• Frank E. Wilson (politician) (1857–1935), U.S. Representative from New York
• Frank J. Wilson (1887–1970), IRS agent who helped convict Al Capone
• Frank Woodrow Wilson (1923–2013), American businessman, lawyer, and politician
• Frank Wilson (diplomat) (born 1946), New Zealand diplomat
• Frank Worthington Wilson, Canadian politician

• Frank Wilson (baseball) (1901–1974), Major League Baseball outfielder
• Frank Wilson (footballer) (1904–?), Scottish footballer with Hamilton Academical
• Frank Wilson (umpire) (1890–1928), American baseball umpire
• Frank Wilson (American football) (born 1973), American college football coach
• Frank Wilson (rugby, born 1944), rugby union and rugby league footballer of the 1960s and 1970s
• Frank Wilson (rugby union, born 1885) (1885–1916), New Zealand rugby union player killed in WWI
• Frank Wilson (rugby union, born 1952), Irish rugby union player

• Frank E. Wilson (bishop) (1885–1944), first Bishop of the Episcopal Diocese of Eau Claire
• F. P. Wilson (1889–1963), professor of English literature
• Frank Norman Wilson (1890–1952), American cardiologist

• Francis Wilson (disambiguation)