Saint Francis of Assisi was a friar and the founder of the Order of Friars Minor.

Saint Francis of Assisi may also refer to:

• Saint Francis of Assisi Cathedral (disambiguation)
• St. Francis of Assisi Church (disambiguation)

• St. Francis of Assisi Elementary, a Catholic elementary school in Vancouver, Canada
• St Francis of Assisi Catholic College, a mixed Roman Catholic secondary school in Walsall, England
• The Academy of St Francis of Assisi, a secondary school in Liverpool, England
• St. Francis of Assisi Convent High School, a high school in Navsari, Gujarat, India
• Saint Francis of Assisi College, a system of private, Catholic-oriented but non-sectarian Philippine schools
• St. Francis of Assisi Elementary School, a Catholic school within the Archdiocese of Louisville, United States

• Saint Francis of Assisi Parish, Karachi, Pakistan
• Saint Francis of Assisi (film), a 1944 Mexican film
• Francis of Assisi (film), a 1961 film
• Francesco di Assisi, a 1966 film
• Saint Francis of Assisi, a 1923 book by G. K. Chesterton

• Sisters of St. Francis of Assisi, a Roman Catholic religious order for women
• Saint François d'Assise, a 1983 opera by Olivier Messiaen