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File:Schematic representation of DREADD.jpg

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Summary

Description
English: Figure 1. Schematic overview of how different variants of DREADDs (hM3Dq and hM4Di) can be used to activate and also inhibit groups of neurons using CNO. The figure also shows achetylcholine’s (ACh) inhibitory effects on CNO.
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Source https://ecampusontario.pressbooks.pub/neurosciencecdn/chapter/3-4-chemogenetic-methods-to-examine-the-brain-and-behaviour/
Author University of Toronto

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Receptor activated solely by a synthetic ligand

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inception

1 October 2023

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