FLRT2

FLRT2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4V2C, 4V2D
Identifiers
Aliases	FLRT2, fibronectin leucine rich transmembrane protein 2
External IDs	OMIM: 604807; MGI: 3603594; HomoloGene: 8291; GeneCards: FLRT2; OMA:FLRT2 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	85,654,428 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	95,751,989 bp
RNA expression pattern
	Top expressed in
	Top expressed in
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
	Sources:Amigo / QuickGO
Orthologs
	23768
	399558
	ENSG00000185070
	ENSMUSG00000047414
	O43155
	Q8BLU0
	NM_001346143; NM_001346144; NM_001346145; NM_001346146; NM_013231
	NM_201518
	NP_001333072; NP_001333073; NP_001333074; NP_001333075; NP_037363
	NP_958926
	Wikidata
View/Edit Human	View/Edit Mouse

Fibronectin leucine-rich repeat transmembrane protein FLRT2 is a protein that in humans is encoded by the FLRT2 gene.^[5]^[6]^[7]

Function

This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRT family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000185070 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000047414 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lacy SE, Bönnemann CG, Buzney EA, Kunkel LM (December 1999). "Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins". Genomics. 62 (3): 417–26. doi:10.1006/geno.1999.6033. PMID 10644439.
^ Haines BP, Wheldon LM, Summerbell D, Heath JK, Rigby PW (September 2006). "Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development". Developmental Biology. 297 (1): 14–25. doi:10.1016/j.ydbio.2006.04.004. PMID 16872596.
^ ^a ^b "Entrez Gene: FLRT2 fibronectin leucine rich transmembrane protein 2".

Zhang Z, Henzel WJ (October 2004). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Science. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
Ishikawa K, Nagase T, Nakajima D, Seki N, Ohira M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (October 1997). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 4 (5): 307–13. doi:10.1093/dnares/4.5.307. PMID 9455477.
Bonaldo MF, Lennon G, Soares MB (September 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000185070 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000047414 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10644439-5] Lacy SE, Bönnemann CG, Buzney EA, Kunkel LM (December 1999). "Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins". Genomics. 62 (3): 417–26. doi:10.1006/geno.1999.6033. PMID 10644439.

[pmid16872596-6] Haines BP, Wheldon LM, Summerbell D, Heath JK, Rigby PW (September 2006). "Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development". Developmental Biology. 297 (1): 14–25. doi:10.1016/j.ydbio.2006.04.004. PMID 16872596.

[entrez-7] "Entrez Gene: FLRT2 fibronectin leucine rich transmembrane protein 2".

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[5]

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[7]

Fahrer / Team für die Suche eingeben:

Fahrer / Team für die Suche eingeben:

Langbahn Team – Weltmeisterschaft

FLRT2

Function

References

Further reading