Ex Machina is a portion of the phrase deus ex machina, meaning "god from the machine". It may refer to:

• Ex Machina (comics), a comic book series by Brian K. Vaughan and Tony Harris
• Ex Machina (Star Trek), a 2004 Star Trek novel by Christopher L. Bennett

• Appleseed Ex Machina, a 2007 anime film and the sequel to the 2004 film Appleseed
• Ex Machina (film), a 2014 British science fiction film

• Ex Machina, a 1998 EP by American surf rock group Man or Astro-man?
• Ex machina (group), German music group

• Ex Machina (role-playing game), a post cyberpunk role-playing game
• Ex Machina (theatre company), a theatre company founded by director Robert Lepage in Quebec City, Canada

• Deus ex machina (disambiguation)