Equus may refer to:

• Equus (genus), a genus of animals including horses, donkeys and zebras
• Equus (play), a play by Peter Shaffer
• Equus (film), a film adaptation of the Peter Shaffer play
• Equus (comics), a comic book character; an opponent of Superman
• Equus (magazine), American monthly lifestyle magazine for horse enthusiasts

• "Equus", a composition for concert band by Eric Whitacre
• "Equus", a song by Blonde Redhead from Misery Is a Butterfly
• "Equus", a song by the Cherry Poppin' Daddies off their 1994 album Rapid City Muscle Car

• Equus Automotive, an American muscle car producer
• Hyundai Equus, Korean automobile model built by Hyundai Motor Company
• Vauxhall Equus, 1978 concept car

• Eques (ancient Rome), a member of one of the noble classes of Ancient Rome
• Equestrian (disambiguation)