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Enterodiol

Enterodiol
Names
Preferred IUPAC name
(2R,3R)-2,3-Bis[(3-hydroxyphenyl)methyl]butane-1,4-diol
Other names
(−)-Enterodiol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.162.704 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C18H22O4/c19-11-15(7-13-3-1-5-17(21)9-13)16(12-20)8-14-4-2-6-18(22)10-14/h1-6,9-10,15-16,19-22H,7-8,11-12H2/t15-,16-/m0/s1 ☒N
    Key: DWONJCNDULPHLV-HOTGVXAUSA-N ☒N
  • InChI=1/C18H22O4/c19-11-15(7-13-3-1-5-17(21)9-13)16(12-20)8-14-4-2-6-18(22)10-14/h1-6,9-10,15-16,19-22H,7-8,11-12H2/t15-,16-/m0/s1
    Key: DWONJCNDULPHLV-HOTGVXAUBO
  • C1=CC(=CC(=C1)O)C[C@@H](CO)[C@@H](CC2=CC(=CC=C2)O)CO
Properties
C18H22O4
Molar mass 302.370 g·mol−1
Appearance colorless
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Enterodiol is an organic compound with the formula [HOC6H4CH2CH(CH2OH)]2.

It is formed by the action of intestinal bacteria on lignan precursors. As such it is sometimes classified as a enterolignan or mammalian lignan.[1][2] Elevated levels of enterodiol in urine are attributed consumption of tea and other lignan-rich foods.[3]

References

  1. ^ Adlercreutz, Herman (2007). "Lignans and Human Health". Critical Reviews in Clinical Laboratory Sciences. 44 (5–6): 483–525. doi:10.1080/10408360701612942. PMID 17943494. S2CID 31753060.
  2. ^ Lampe JW (2003). "Isoflavonoid and lignan phytoestrogens as dietary biomarkers". J Nutr. 133 (Suppl 3): 956S–964S. doi:10.1093/jn/133.3.956S. PMID 12612182.
  3. ^ Adlercreutz, H.; Honjo, H.; Higashi, A.; Fotsis, T.; Hämäläinen, E.; Hasegawa, T.; Okada, H. (1991). "Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese Diet". The American Journal of Clinical Nutrition. 54 (6): 1093–1100. doi:10.1093/ajcn/54.6.1093. PMID 1659780.
Quelle: https://en.wikipedia.org/wiki/Enterodiol