En route may refer to:

• En Route (novel), an 1895 novel by Joris-Karl Huysmans
• En Route (film), a 2004 German movie directed by Jan Krüger
• En-route chart, in aeronautics
• enRoute (credit card), Air Canada's credit card division, now merged with Diners Club
• enRoute (magazine), Air Canada's in-flight magazine
• Air Canada enRoute Film Festival
• "V Put" ("En Route"), a 1954 Soviet song by Vasili Solovyov-Sedoi, Les Chœurs De L'Armée Soviétique
• En Route (album), a 1995 album by Moebius and Plank
• En Route, an album by Orquesta Aragón, 2011