EA-2192
| |
| Names | |
|---|---|
| Preferred IUPAC name S-{2-[Di(propan-2-yl)amino]ethyl} methylphosphonothioate | |
| Other names Diisopropylaminoethyl methyl thiolophosphonate | |
| Identifiers | |
3D model (JSmol) |
|
| ChemSpider | |
PubChem CID |
|
| UNII | |
CompTox Dashboard (EPA) |
|
| |
| Properties | |
| C9H22NO2PS | |
| Molar mass | 239.31 g·mol−1 |
| Appearance | White solid |
| Very soluble | |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards |
Extremely toxic |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
630 μg/kg (Rat, oral) 18 μg/kg (Rat, iv) 50 μg/kg (Mouse, iv) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
EA-2192 is an extremely toxic degradation product of the VX, a very potent nerve agent.[1][2] It is a white solid that is very soluble and stable in water.
EA-2192 is an extremely potent acetylcholinesterase inhibitor. It is almost as toxic as VX itself.[3]
EA-2192 behaves similar to aged soman as it is the dealkylated form of VX and cannot be reversed with common oxime reactivators.
See also
References
- ^ Ellison, D. Hank (2007). Handbook of chemical and biological warfare agents (2nd ed.). Boca Raton, Fla.: CRC. ISBN 9780849314346.
- ^ Hoenig, Steven L. (2007), Compendium of Chemical Warfare Agents, Springer, ISBN 978-0-387-34626-7
- ^ Munro, NB; Talmage, SS; Griffin, GD; Waters, LC; Watson, AP; King, JF; Hauschild, V (December 1999). "The sources, fate, and toxicity of chemical warfare agent degradation products". Environmental Health Perspectives. 107 (12): 933–74. doi:10.1289/ehp.99107933. PMC 1566810. PMID 10585900.