Duele (Spanish for "It Hurts") may refer to:

• "Duele" (Chenoa song), 2009
• "Duele" (Reik and Wisin & Yandel song), 2019
• "Duele", a 2017 song by Bomba Estéreo from Ayo
• "Duele", a 2004 song by Lu
• "Duele", a 2015 song by Natalia Lafourcade from Hasta la Raíz
• "Duele", a 2020 song by Tini and John C from Tini Tini Tini
• "Duele", a 2002 song by Tito El Bambino from A la Reconquista
• "Dueles", a 2015 song by Jesse & Joy from Un Besito Más