Doheny is an Irish surname. Notable people with the surname include:

• Ed Doheny (1873–1916), American baseball player
• Edward Laurence Doheny (1856–1935), American oil tycoon
• Jer Doheny (1874–1929), Irish sportsman
• John Doheny (born 1953), American jazz musician
• Lawrence Doheny (1924–1982), American television director
• Michael Doheny (1805–1863), Irish writer and politician
• Ned Doheny, American singer, songwriter and guitarist

• Doheny & Nesbitt – Victorian Pub in Dublin, Ireland
• Doheny Eye Institute, a nonprofit ophthalmic research institute.
• Doheny Drive, a major north/south thoroughfare of Beverly Hills and West Hollywood, California
• Doheny State Beach, a California state park
• Doheny Library, on the campus of the University of Southern California
• Doheny Plaza, high-rise building in West Hollywood, California.
• Greystone Mansion, also known as the Doheny Mansion, Beverly Hills, California
• Doheny, one of the two campuses of Mount St. Mary's College, Los Angeles, California
• Dohenys GAA, a Gaelic Athletic Association club in Dunmanway, County Cork, Ireland