Di Cocco (also di Cocco and DiCocco) is a surname. Notable people with the name include:

• Caroline Di Cocco, Italian-Canadian politician
• Francesco Di Cocco (1900–1989), Italian painter
• Giampaolo di Cocco (born 1947), Italian artist, architect and writer
• Paul DiCocco Sr. (1924–1989), American mobster associate

• DiCicco, a list of people with a similar surname