DiCicco (also Di Cicco and Dicicco) is a surname. Notable people with the name include:

• Bobby Di Cicco, Italian-American actor
• Dennis di Cicco (born 1950), American astronomer and discoverer of minor planets
• Domenick DiCicco (1963–2024), American politician from New Jersey
• Frank DiCicco (born c. 1946), American politician on the Philadelphia City Council
• Jessica DiCicco (born 1980), American voice, film and television actress
• Pat DiCicco (1909–1978), American agent, movie producer, and actor
• Pier Giorgio Di Cicco (1949–2019), Italian-Canadian poet
• Sue DiCicco (born 1959), American sculptor, children's book author and illustrator
• Tony DiCicco (1948–2017), American soccer player, coach, and commentator

• 3841 Dicicco, named after Dennis di Cicco
• De Cicco v. Schweizer, 1917 American court case concerning privity of contract and consideration
• DeCicco Building, historic building in Portland, Oregon
• De Cecco, Italian pasta company
  • De Cecco (surname)
• Di Cocco, a list of people with the surname DiCocco and similar