The San Xavier Indian Reservation (O’odham: Wa:k) is an Indian reservation of the Tohono O’odham Nation located near Tucson, Arizona, in the Sonoran Desert. The San Xavier Reservation lies in the southwestern part of the Tucson metropolitan area and consists of 111.543 sq mi (288.90 km²) of land area, about 2.5 percent of the Tohono O’odham Nation. It had a 2000 census resident population of 2,053 persons, or 19 percent of the Tohono O’odham population.

The reservation is home to a Spanish mission, Mission San Xavier del Bac, which was built in between 1783 and 1797. It is a National Historic Landmark, and has been in continuous use for over 200 years. It was built by Tohono O’odham laborers.

The tribe also operates three casinos, two of which are on the San Xavier section of the reservation. The casino facilities, known as the Desert Diamond and Golden Ha:ṣañ, feature slot machines, table games, video blackjack and other forms of gambling. There is also a buffet. The facility also features a theater for live entertainment.

Tohono O'odham Nation 7350 S. Nogales Highway, Tucson 1 mile south of Valencia Rd on Nogales Highway.^[1]

1100 W. Pima Mine Rd, Sahuarita South of Tucson at I-19 and Exit 80 (Pima Mine Rd).^[1]

Highway 86, Why 11⁄2 miles east of Why, AZ on Highway 86.^[1]

This casino is located at the extreme western end of the main reservation (formerly known as the Papago Indian Reservation).

Northern Ave and Loop 101 Glendale, AZ. Future site of the West Valley Resort at Northern Avenue.^[2]

• Tohono O'odham
• Indian reservation
• Black Mountain (Pima County, Arizona)

• Census Tract 9409 (San Xavier Reservation), Pima County, Arizona; Tohono O'odham Reservation and Off-Reservation Trust Land, Arizona United States Census Bureau

32°03′14″N 111°04′12″W / 32.054°N 111.070°W / 32.054; -111.070