Deep Space may refer to:

• Deep Space Network (disambiguation), international network of satellite ground stations
  • Goldstone Deep Space Communications Complex, satellite ground station in California, US
  • Madrid Deep Space Communication Complex, satellite ground station in Spain
  • Canberra Deep Space Communication Complex, satellite ground station in Australia
• Deep Space 1, spacecraft
• Deep Space 2, two highly advanced miniature probes

• Empty regions of the universe in outer space
• Interstellar space
• Intergalactic space

• Deep Space (film), a 1988 horror sci-fi movie
• Deep Space (music), Saturday late night/early morning radio show on WGPR 107.5 FM in Detroit
• Deep Space (collection), a 1954 collection of short stories by Eric Frank Russell
• Deep Space (EP), an EP by Eisley
• Deep Space, a video game company and subsidiary of Sony Computer Entertainment
• Deep Space Industries, an American company developing and producing spacecraft technology
• "Deep Space", a song by Blank Banshee from the album Blank Banshee 0
• "Deep Space", a song by Sub Focus from the album Sub Focus

• Deep space exploration