David or Dave Cole may refer to:

• David L. Cole (1902–1978), American labor mediator
• David Cole (1928–2003), Welsh journalist, later editor and chairman of the Western Mail
• Dave Cole (baseball) (1930–2011), American baseball player
• David Cole (diplomat), British diplomat
• David C. Cole (born 1952), entrepreneur and philanthropist
• David D. Cole (born 1958), legal scholar and legal director of the ACLU
• David N. Cole (active since 1980), American music producer
• David Cole (journalist) (born 1968), American Holocaust denier and journalist
• David Cole (record producer) (1962–1995), American record producer, songwriter, one half of the duo C+C Music Factory
• David Cole (footballer) (born 1962), English footballer
• David Cole (politician), American politician
• David Cole, badminton player that played in 1991 IBF World Championships – Men's singles
• Dave Cole (artist) (born 1975), American visual artist
• David R. Cole (active since 2004), Australian researcher at the University of Western Sydney

• David Cole House (built 1890) in Portland, Oregon, USA
• David Cole Observatory (established 2007) in Massachusetts, USA
• David Coles (disambiguation)
• Cole (surname)