Comatose may refer to:

• Being in a state of a coma, or being unconscious
• Comatose (album), a 2006 album by Skillet
  • "Comatose" (Skillet song), the title song
• "Comatose", a song by Ayreon from 01011001, 2008
• "Comatose", a song by Bad Wolves from Dear Monsters, 2021
• "Comatose", a song by Coheed and Cambria from the album Vaxis – Act II: A Window of the Waking Mind, 2022
• "Comatose", a song by Chimaira from Chimaira, 2005
• "Comatose", a song by Depeche Mode from Exciter, 2001
• "Comatose", a song by Front Line Assembly from (FLA)vour of the Weak, 1997
• "Comatose", a song by jxdn, 2020
• "Comatose", a song by Mikky Ekko from Time, 2015
• "Comatose", a song by Nina Sky from Nicole and Natalie, 2012
• "Comatose", a song by Northlane from Discoveries, 2011
• "Comatose", a song by P.M. Dawn from Of the Heart, of the Soul and of the Cross: The Utopian Experience, 1991
• "Comatose", a song by Pearl Jam from Pearl Jam, 2006
• "Comatose", a song by Threat Signal from Threat Signal, 2011