Christophe is a male given name and a surname. It is a French variant of Christopher.

• Christophe (Georges Colomb) (1856–1945), French comic strip artist and botanist
• Cristophe (hairstylist) (born 1958), Belgian hairstylist
• Christophe (singer) (1945–2020), French singer

• Christophe Barratier, French filmmaker
• Christophe Beck, Canadian composer
• Christophe Dumaux, French opera singer
• Christophe Gans, French filmmaker
• Christophe Keckeis, chief of the Swiss Armed Forces
• Christophe Lemaitre, French sprinter
• Christophe Moreau, French cyclist
• Christophe Naegelen (born 1983), French politician
• Christophe Revault (1972–2021), French footballer
• Christophe Rinero, French cyclist
• Christophe Soulé, French mathematician

• Anne Christophe, French psychologist
• Didier Christophe (born 1956), French footballer, managing Pau FC
• Ernest Christophe (1827–1892), French sculptor
• Eugène Christophe (1885–1970), French cyclist
• Françoise Christophe (1923–2012), French actress
• François-Ferdinand Christophe (1794–1805), Haitian prince, son of Henri
• Fredler Christophe (born 2002), Haitian footballer
• Henri Christophe (1767–1820), Haitian Revolution leader, first King of Haiti
• Jean-François Christophe (born 1987), French footballer
• Joseph Christophe (1662–1748), French painter
• Marcel Christophe (born 1974), Luxembourgian footballer
• Paul Christophe (born 1971), French politician
• Pierre Christophe (1880–1971), French sculptor
• Robert Christophe (1938–2016), French Olympic swimmer

• Christof, given name
• Christoph, given name and surname