Charles Bryant may refer to:

• Charles Bryant (actor) (1879–1948), British actor
• Charles David Jones Bryant (1883–1937), Australian artist
• Charles Ernest William Bryant (1902–1960), Australian barrister and ornithologist
• Charles Gyude Bryant (1949–2014), Liberian politician
• Charles G. Bryant (1803–1850), architect, soldier, adventurer, and American expansionist
• Charles W. "Chuck" Bryant (born 1971), American podcaster and co-host of Stuff You Should Know