Carlos Calderón may refer to:

• Carlos Calderón (boxer) (born 1955), Puerto Rican boxer
• Carlos Calderón (fencer) (born 1947), Mexican Olympic fencer
• Carlos Calderón (Ecuadorian footballer) (born 1959), Ecuadorian footballer and manager
• Carlos Calderón (Mexican footballer) (1934–2012), Mexican footballer
• Carlos Calderón (Salvadoran footballer) (born 1986), Salvadoran footballer
• Carlos Calderón (Spanish footballer) (born 1995), Spanish footballer
• Carlos Calderón Fajardo (1946–2015), Peruvian journalist