Brambilla is an Italian surname derived from Val Brembana in Italy. In the 1700s the name travelled to a small town in the state of Jalisco Mexico and was modified to Brambila to retain pronunciation in Spanish.

As of 2014, 84.6% of all known bearers of the surname Brambilla were residents of Italy (frequency 1:1,475), 8.5% of Brazil (1:49,339) and 3.6% of Argentina (1:24,509).

In Italy, the frequency of the surname was higher than national average (1:1,475) in only one region: Lombardy (1:246).^[1]

• Edy Brambila (born 1986), Mexican footballer
• Elena Brambilla (1942–2018), Italian historian
• Ernesto Brambilla, Italian motorcycle and racecar driver
• Fernando Brambila (1763-1834), Italian-Spanish painter and engraver
• Francesco Brambilla, Italian sculptor of the Renaissance period
• Franco Brambilla (archbishop) (1923–2003), Vatican diplomat
• Gianluca Brambilla, Italian racing cyclist
• Giovanni Alessandro Brambilla, Italian physician
• Giovanni Battista Brambilla, Italian painter
• Giuseppina Brambilla, Italian opera singer, sister of Marietta and Teresa
• Gustavo Brambila (born 1953), Mexican-American winemaker
• Leticia Brambila Paz, Mexican mathematician
• Marco Brambilla, Italian-born Canadian artist and filmmaker.
• Maria Brambilla, Italian ballerina, stage name Sofia Fuoco
• Marietta Brambilla, Italian opera singer, sister of Giuseppina and Teresa
• Massimo Brambilla, Italian football player
• Michela Vittoria Brambilla, Italian politician and businesswoman
• Nora Brambilla, Italian and German physicist
• Pierre Brambilla, French road bicycle racer
• Sofía Brambilla (born 1980), Argentine politician
• Teresa Brambilla, Italian opera singer, sister of Giuseppina and Marietta
• Teresina Brambilla, Italian opera singer, niece of Giuseppina, Marietta, and Teresa
• Vittorio Brambilla, Italian Formula One driver

• 640 Brambilla, a minor planet orbiting the Sun
• Brembilla (disambiguation)