Bozhou or Bo Prefecture (亳州) was a zhou (prefecture) in imperial China, centering on modern Bozhou, Anhui, China. It existed (intermittently) from the 6th century until 1912.

The modern prefecture-level city Bozhou, created in 1986, retains its name.

The administrative region of Bo Prefecture in the Tang dynasty is in the border area of modern northern Anhui and southeastern Henan. It probably includes parts of modern:

• Under the administration of Bozhou, Anhui:
  • Bozhou
  • Mengcheng County
• Under the administration of Shangqiu, Henan:
  • Yongcheng
• Under the administration of Zhoukou, Henan:
  • Luyi County

In the early 1100s during the Song dynasty, there were 130,119 households and 183,581 people.^[1]

• Qiao Commandery

• (in Chinese) Toqto'a; et al., eds. (1345). Song Shi (宋史) [History of Song].
• Shi Weile, ed. (2005). Zhongguo Lishi Diming Da Cidian (中国历史地名大词典) [Large Dictionary of Chinese Historical Place Names] (in Chinese). China Social Sciences Press. p. 2179. ISBN 7-5004-4929-1.