Berthier is a surname. Notable people with the surname include:

• Alexandre Berthier (1638–1708), French officer posted to Canada
• Clément Berthier (born 2000), French para table tennis player
• Ferdinand Berthier (1803-1886), French writer, educator, and advocate for societal inclusion of those experiencing Deafness
• Guillaume-François Berthier (1704–1782), Jesuit writer
• Jacques Berthier (1923–1994), Taizé composer
• Jacques Berthier (1916 – 2008), French actor
• Jean-Marie Berthier (1940 - 8 August 2017), French poet
• Louis-Alexandre Berthier (1753–1815), Marshal of France under Napoleon
• Pierre Berthier (1782–1861), geologist