Bone morphogenetic protein 8A

BMP8A
Identifiers
Aliases	BMP8A, entrez:353500, bone morphogenetic protein 8a, OP-2
External IDs	MGI: 104515; HomoloGene: 135983; GeneCards: BMP8A; OMA:BMP8A - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	39,529,869 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	123,237,045 bp
RNA expression pattern
	Top expressed in
	Top expressed in
	More reference expression data
	n/a
Gene ontology
Molecular function
Cellular component
Biological process
	Sources:Amigo / QuickGO
Orthologs
	353500
	12163
	ENSG00000183682
	ENSMUSG00000032726
	Q7Z5Y6
	P34821
	NM_181809
	NM_001256019; NM_007558
	NP_861525
	NP_001242948; NP_031584
	Wikidata
View/Edit Human	View/Edit Mouse

Bone morphogenetic protein 8A (BMP8A) is a protein that in humans is encoded by the BMP8A gene.^[5]

BMP8A is a polypeptide member of the TGFβ superfamily of proteins. It, like other bone morphogenetic proteins (BMPs), is involved in the development of bone and cartilage. BMP8A may be involved in epithelial osteogenesis. It also plays a role in bone homeostasis. It is a disulfide-linked homodimer.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000183682 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032726 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: bone morphogenetic protein 8a".

Human BMP8A genome location and BMP8A gene details page in the UCSC Genome Browser.

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Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.