Arthur Hughes may refer to:

• Arthur Hughes (American actor) (1894–1982), American actor on the stage, radio and films
• Arthur Hughes (artist) (1832–1915), English painter and illustrator
• Arthur Hughes (British actor) (born 1992), British actor on stage, radio and television
• Arthur Foord Hughes (1856–1934), English artist
• Arthur Wellesley Hughes (1870–1950), Canadian musician and composer
• Frank Randle (1901–1957), English comedian, born as Arthur Hughes

• Art Hughes (American soccer) (born 1965), American soccer player
• Art Hughes (Canadian soccer) (1930–2019), Canadian soccer player
• Arthur Hughes (English footballer) (1883–1962), English footballer for Bolton Wanderers, Southampton and Manchester City
• Arthur Hughes (rugby union) (1924–2005), New Zealand rugby union player
• Arthur Hughes (Scottish footballer) (1927–2015), Scottish footballer for Grimsby Town and Gillingham
• Arthur Hughes (Welsh footballer) (1884–1970), Chirk F.C. and Wales international footballer

• Arthur Hughes (archbishop) (1902–1949), British prelate of the Catholic Church
• Arthur Hughes (politician) (1885–1968), Australian politician
• Arthur William Hughes (1883–1964), British businessman in Hong Kong
• Arthur Hayden Hughes (born 1939), United States Ambassador to Yemen, 1991–1994

• Hughes (surname)