Antigonia may refer to:

• Antigonia (Chaonia), near Saraqinisht, southern Albania
  • Archaeological National park of Antigonea
• Antigonia (Paeonia), in Paeonia, Macedon
• Antigonia Psaphara, in Crucis, Chalcidice, Greece
• Antigonia (Syria), in Seleucis, Syria, now near Antakya, Hatay Province, Turkey
• Alexandria Troas or Antigonia, in Troas, Asia Minor, now Eski Stambul, Çanakkale Province, Turkey
• Diocese of Antigonia, a former see in the Roman province Hellespontus
• Nicaea or Antigonia, Bithynia, now İznik, Bursa Province, Turkey
• Mantinea or Antigonia, Arcadia, Greece

• Antigonia (fish), a genus of fish