Andrew or Andy Kelly may refer to:

• Andrew Kelly (Australian politician) (1854–1913), New South Wales politician
• Andy Kelly (hurler) (1898–?), Irish hurler
• Andy Kelly (rugby league) (born 1960), English rugby league footballer
• Andy Kelly (American football) (born 1968), American football quarterback
• Andrew Kelly (rugby union, born 1981), Scottish rugby union player for Glasgow Warriors
• Andrew Kelly (rugby union, born 1982), Scottish rugby union player for Edinburgh Rugby
• Andrew Kelly (footballer) (born 1984), English footballer
• Andrew Kelly (bowls) (born 1989), New Zealand lawn and Indoor bowler
• Andrew Kelly (Redwater), fictional character
• Andrew Kelly (sprinter), winner of the 300 yards at the 1917 USA Indoor Track and Field Championships

• Andrew J. Kelley, American Civil War soldier and Medal of Honor recipient
• Andrew Kelley, designer of the programming language Zig
• Andrew Kelley (actor), actor in the 1992 Dutch film For a Lost Soldier