Alone Again may refer to:

• Alone Again (album), by George Jones, 1976
• "Alone Again" (Alyssa Reid song), 2010
• "Alone Again" (Dokken song), 1985
• "Alone Again" (The Weeknd song), 2020
• "Alone Again", a song by the Bee Gees from 2 Years On, 1970
• "Alone Again", a song by the Slackers from The Question, 1998
• "Alone Again", a song by Teenager
• "Alone Again", an unreleased song by Kylie Minogue from White Diamond: A Personal Portrait of Kylie Minogue soundtrack

• Alone, Again, a 1975 album by Paul Bley
• Alone (Again), a 1977 album by Bill Evans
• Alone Again Or, a 1967 song by the band Love
• "Alone Again (Naturally)", a 1972 song by Gilbert O'Sullivan
• Alone Again (Naturally) (album), a 1972 album by Andy Williams